Squeezing out in a “tug of war”: The role of myosin in neural stem cell delamination
نویسندگان
چکیده
Neural stem cells or neuroblasts in the Drosophila melanogaster embryo delaminate as single cells from the embryonic epidermis to give rise to the nervous system. Using this accessible system to examine the molecular mechanisms of cell ingression at a high temporal and spatial resolution, in this issue, Simões et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608038) reveal that myosin-driven anisotropic junction loss and apical constriction are the main drivers of this process.
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عنوان ژورنال:
دوره 216 شماره
صفحات -
تاریخ انتشار 2017